The WestNile 4K Project is a partnership between West Nile virus surveillance laboratories and academic institutions across the United States. Our main goal is to provide real-time high definition reconstructions of the micro- (e.g., city/county) and macro-level (e.g., state/country) spread and evolution of West Nile virus by sequencing more than 8,000 virus genomes from infected birds, mosquitoes, and patients.
The data generated as part of this project will be immediately released to the public, and along with other entomological data, will be used to uncover local transmission dynamics. Analyses and visualizations will also be made publicly available in real-time as data are produced. As little progress has been made in effectively controlling West Nile virus outbreaks since its emergence in the United States two decades ago, our goal is to use fine-scale genomics-based transmission networks and extensive experimental studies to inform public health responses and help design future targeted control measures.
To learn more about the first twenty years of West Nile virus spread and evolution in the Americas and some of the background behind the WestNile 4K Project, read our recent review in PLOS Pathogens.
>1000
Genomes
1
Countries
34
States
49
Institutions
>100
Collaborators
Recent Data Releases
Iowa
Collaboration and Data Sources We received 194 samples of RNA extracted from mosquito pools that tested positive for West Nile virus from Ryan Smith from Iowa State University. 117 samples were selected and had suitable genome coverage after sequencing for phylogenetic analysis. All samples came from Iowa between the years 2016 and 2020. In this update, we highlight the sequencing…
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Colorado
Collaboration and Data Sources We received 626 samples of RNA extracted from mosquito pools that tested positive for West Nile virus from Greg Ebel, Reyes Murrieta, Joseph Fauver, and Michael C. Young from Colorado State University. 94 samples were selected and had suitable genome coverage after sequencing for phylogenetic analysis. Samples came from Larimer County between the years 2013 and…
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Minnesota
Collaboration and Data Sources We received 120 samples of RNA extracted from birds that tested positive for West Nile virus from David Neitzel from the Minnesota Department of Health. 113 samples were selected and had suitable genome coverage after sequencing for phylogenetic analysis. Samples came from 39 counties and the years 2002-2005. In this update, we highlight the sequencing results…
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Partners
City of Chicago / CDPH Vector Control Program
Alex Westrich
Claudia Blanco
Raed Mansour
City of Sioux Falls Health
Denise Patton
Champaign-Urbana Public Health District
Jeff Blackford
Colorado State University
Greg Ebel
Reyes Murrieta
Joseph Fauver
Michael C. Young
Connecticut Agricultural Experiment Station
Phil Armstrong
John Shepard
Ted Andreadis
John Anderson
Eastern Washington University
Krisztian Magori
Florida Department of Health
Andrea Morrison
Grand Forks Public Health Department
Todd Hanson
Idaho Department of Health and Welfare
Vonnita Barton
Indiana State Department of Health
Bryan Price
Iowa Department of Public Health
Ann Garvey
Julie Coughlin
Iowa State University
Ryan Smith
Kansas Biological Survey / The University of Kansas
Christopher Rogers
Kansas Department of Health and Environment
Ingrid Garrison
Amie Cook
Louisiana Animal Disease Diagnostic Laboratory / Louisiana State University
Udeni Balasuriya
Rebecca Christofferson
Tarra Harden
Zelalem Mekuria
Laura Peak
Alma Roy
Keith Strother
Maine Medical Center Research Institute
Chuck Lubelczyk
Metropolitan Mosquito Control District
Kirk Johnson
Michigan State University
Michael Kaufman
Ned Walker
Trisha Dubie
Minnesota Department of Health
David Neitzel
Mississippi State Department of Health
Wendy Varnado
Nebraska Department of Health and Human Services
Jeff Hamik
Nebraska Public Health Laboratory / University of Nebraska Medical Center
Pete Iwen
Vicki Herrera
Emily McCutchen
New Hampshire Public Health Laboratories
Denise Bolton
Abigail Mathewson
Carolyn Fredette
Rebecca Lovell
Amy Kutschke
North Shore Mosquito Abatement District
Mark Clifton
Ohio Department of Health
Leeanne Garrett
Kevin Sohner
Jim Scott
Oregon Veterinary Diagnostic Laboratory / Oregon State University
Donna Mulrooney
Manoj Pastey
Justin Sanders
Andree Hunkapiller
Noah Lawler
Sarah Greene
Pennsylvania Department of Agriculture
Michael Hutchinson
Pennsylvania Department of Environmental Protection
Keith Price
San Diego Vector Control
Nikos Gurfield
Saran Grewal
Jorell Tuncap
Scripps Research
Kristian Andersen
Nate Matteson
Karthik Gangavarapu
Refugio Robles
South Dakota Public Health Laboratory
Chris Carlson
Southern Nazarene University
Caio França
St. Louis County Vector Control
Tony Patullo
Texas Department of State Health Services
Bethany Bolling
University of California, Davis
Chris Barker
Sarah Wheeler
Ying Fang
Lark Coffey
William Reisen
University of California, Los Angeles
Marc Suchard
University of Georgia
Daniel Mead
Isabel Ott
University of Illinois at Urbana-Champaign
Chris Stone
University of Iowa / State Hygienic Laboratory
Lucy Desjardin
Jeff Benfer
University of South Alabama
Jonathan Rayner
Ryan Wood
John McCreadie
University of Tennessee
Becky Trout-Fryxell
University of Wisconsin-Madison
Lyric Bartholomay
Susan Paskewitz
Vector Disease Control International
Broox Boze
Alex Westrich
Mike Mangano
Will Schlatmann
Vermont Department of Health Laboratory
Christine Matusevich
Patti Casey
Eliza Doncaster
Washington State Department of Health
Amy Salamone
Elizabeth Dykstra
Erin Knutson
Anne Duffy
Washington State University
Dan Bradway
Becca Wolking
Marla Francis
Yale School of Public Health
Nate Grubaugh
Chantal Vogels
Anderson Brito
Mary Petrone
Managing Partners
