Overview

The WestNile 4K Project is a partnership between West Nile virus surveillance laboratories and academic institutions across the United States. Our main goal is to provide real-time high definition reconstructions of the micro- (e.g., city/county) and macro-level (e.g., state/country) spread and evolution of West Nile virus by sequencing more than 8,000 virus genomes from infected birds, mosquitoes, and patients.

The data generated as part of this project will be immediately released to the public, and along with other entomological data, will be used to uncover local transmission dynamics. Analyses and visualizations will also be made publicly available in real-time as data are produced. As little progress has been made in effectively controlling West Nile virus outbreaks since its emergence in the United States two decades ago, our goal is to use fine-scale genomics-based transmission networks and extensive experimental studies to inform public health responses and help design future targeted control measures.

To learn more about the first twenty years of West Nile virus spread and evolution in the Americas and some of the background behind the WestNile 4K Project, read our recent review in PLOS Pathogens.

1108
Genomes
1
Countries
34
States
49
Institutions
109
Collaborators

Recent Data Releases

May 6, 2020 in Data

Colorado

Collaboration and Data Sources We received 626 samples of RNA extracted from mosquito pools that tested positive for West Nile virus from Greg Ebel, Reyes Murrieta, Joseph Fauver, and Michael C. Young from Colorado State University. 94 samples were selected and had suitable genome coverage after sequencing for phylogenetic analysis. Samples came from Larimer County between the years 2013 and…
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January 7, 2020 in Data

Minnesota

Collaboration and Data Sources We received 120 samples of RNA extracted from birds that tested positive for West Nile virus from David Neitzel from the Minnesota Department of Health. 113 samples were selected and had suitable genome coverage after sequencing for phylogenetic analysis. Samples came from 39 counties and the years 2002-2005. In this update, we highlight the sequencing results…
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December 17, 2019 in Data

Illinois

Collaboration and data sources We received 212 samples of RNA extracted from mosquito pools that tested positive for West Nile virus from Alex Westrich, Claudia Blanco, and Raed Mansour from the City of Chicago Department of Public Health. Samples were selected for sequencing from each trap location within the city that we had samples from. 26 samples were ultimately selected…
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Partners

City of Chicago / CDPH Vector Control Program
Alex Westrich
Claudia Blanco
Raed Mansour

City of Sioux Falls Health
Denise Patton

Champaign-Urbana Public Health District
Jeff Blackford

Colorado State University
Greg Ebel
Reyes Murrieta
Joseph Fauver
Michael C. Young

Connecticut Agricultural Experiment Station
Phil Armstrong
John Shepard
Ted Andreadis
John Anderson

Eastern Washington University
Krisztian Magori

Florida Department of Health
Andrea Morrison

Grand Forks Public Health Department
Todd Hanson

Idaho Department of Health and Welfare
Vonnita Barton

Indiana State Department of Health
Bryan Price

Iowa Department of Public Health
Ann Garvey
Julie Coughlin

Iowa State University
Ryan Smith

Kansas Biological Survey / The University of Kansas
Christopher Rogers

Kansas Department of Health and Environment
Ingrid Garrison
Amie Cook

Louisiana Animal Disease Diagnostic Laboratory / Louisiana State University
Udeni Balasuriya
Rebecca Christofferson
Tarra Harden
Zelalem Mekuria
Laura Peak
Alma Roy
Keith Strother

Maine Medical Center Research Institute
Chuck Lubelczyk

Metropolitan Mosquito Control District
Kirk Johnson

Michigan State University
Michael Kaufman
Ned Walker
Trisha Dubie

Minnesota Department of Health
David Neitzel

Mississippi State Department of Health
Wendy Varnado

Nebraska Department of Health and Human Services
Jeff Hamik

Nebraska Public Health Laboratory / University of Nebraska Medical Center
Pete Iwen
Vicki Herrera
Emily McCutchen

New Hampshire Public Health Laboratories
Denise Bolton
Abigail Mathewson
Carolyn Fredette
Rebecca Lovell
Amy Kutschke

North Shore Mosquito Abatement District
Mark Clifton

Ohio Department of Health
Leeanne Garrett
Kevin Sohner
Jim Scott

Oregon Veterinary Diagnostic Laboratory / Oregon State University
Donna Mulrooney
Manoj Pastey
Justin Sanders
Andree Hunkapiller
Noah Lawler
Sarah Greene

Pennsylvania Department of Agriculture
Michael Hutchinson

Pennsylvania Department of Environmental Protection
Keith Price

San Diego Vector Control
Nikos Gurfield
Saran Grewal
Jorell Tuncap

Scripps Research
Kristian Andersen
Nate Matteson
Karthik Gangavarapu
Refugio Robles

South Dakota Public Health Laboratory
Chris Carlson

Southern Nazarene University
Caio França

St. Louis County Vector Control
Tony Patullo

Texas Department of State Health Services
Bethany Bolling

University of California, Davis
Chris Barker
Sarah Wheeler
Ying Fang
Lark Coffey
William Reisen

University of California, Los Angeles
Marc Suchard

University of Georgia
Daniel Mead
Isabel Ott

University of Illinois at Urbana-Champaign
Chris Stone

University of Iowa / State Hygienic Laboratory 
Lucy Desjardin
Jeff Benfer

University of South Alabama
Jonathan Rayner
Ryan Wood
John McCreadie

University of Tennessee
Becky Trout-Fryxell

University of Wisconsin-Madison
Lyric Bartholomay
Susan Paskewitz

Vector Disease Control International
Broox Boze
Alex Westrich
Mike Mangano
Will Schlatmann

Vermont Department of Health Laboratory
Christine Matusevich
Patti Casey
Eliza Doncaster

Washington State Department of Health
Amy Salamone
Elizabeth Dykstra
Erin Knutson
Anne Duffy

Washington State University
Dan Bradway
Becca Wolking
Marla Francis

Yale School of Public Health
Nate Grubaugh
Chantal Vogels
Anderson Brito
Mary Petrone

Managing Partners

ucla

Scripps Research

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